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Information × Registration Number 0212U007189, 0111U010013 , R & D reports Title Research of the antidiabetic properties of mussel extract under streptozotocin - induced diabetes of type 2 popup.stage_title Head Оvsyannikova Tetyana, Registration Date 18-07-2012 Organization Kharkov National University named after V.N. Karazin popup.description2 The research of mussel extract anti-diabetic properties in the experimental strepthozotocin diabetes mellitus. Aim of work - Definition anti-diabetic properties of the drug from the mussels with streptozotocin model of type 2 diabetes and the possibility of correction of metabolic diseases with damaged parts. The object of the investigation where: metabolic correction in the insulin deficiencies during 2 type diabetes mellitus by mussel extract. The subject of the investigation where: - pro/antioxidant balans, bioenergetic processes, metabolism of lipids and sugars, erythrocytes structures of the animals with insulin deficiencies after the mussel ( Mytilus galloprovincialis Lam.) extract supplementation. Methods of investigation: physiological, biophysical, biochemical, morphometrical, mathematical. The mussel extract supplementation ( 400 mg/kg b.w. per os) in animals with the absolute and relative insulin deficiencies produced the glucose - lowering effect during diabetes formation as well as after manifestation of diabetes. The investigation represented that it was bound up with glutathione - dependent antioxidant enzymes normalization and bioenergetic mitochondrial characteristics amelioration. Product Description popup.authors Забеліна І. Коваленко А. popup.nrat_date 2020-04-02 Close