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Information × Registration Number 0212U008239, 0112U004216 , R & D reports Title Pre-clinical studies of toxicity "Kokarnit / Cocarnit (lyophilized powder for solution for injection supplied with solvent 0.5% solution of lidocaine hidrohloridu). popup.stage_title Head Ostapshenko L.I., Registration Date 06-12-2012 Organization Taras Shevchenko Kiev university popup.description2 The results of pre-clinical toxicity studies of the drug "Kokarnit." A study is acute, subacute, chronic, mestnorazdrazhayuschee toxicity. Just investigated embryotoxicity, teratogenicity, perinatal and fetal toxicity, mutagenicity and carcinogenicity in animals. In a study of acute toxicity were determined sredneletalnye dose administered intramuscularly, which accounted for mice 720 (584.76/ 855.24) mg / kg for rats -> 1000 mg / kg. These indicators allow to carry the tool according to the standard classification of toxicity KK Sidorova to the class of low-toxic substances (501 mg / kg <LD50> 5000 mg / kg) - Class IV toxicity. Product Description popup.authors Богун Л.І. Вирченко А.В. Вороніна К.К. Маркевич А.А. Савченко Ю.О. Савченюк А.В. Скочко Н.С. Фалалеєва Т.М. Харченко О.І. popup.nrat_date 2020-04-02 Close
R & D report
Pre-clinical studies of toxicity "Kokarnit / Cocarnit (lyophilized powder for solution for injection supplied with solvent 0.5% solution of lidocaine hidrohloridu).
Head: Ostapshenko L.I.. Pre-clinical studies of toxicity "Kokarnit / Cocarnit (lyophilized powder for solution for injection supplied with solvent 0.5% solution of lidocaine hidrohloridu).. (popup.stage: ). Taras Shevchenko Kiev university. № 0212U008239
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Updated: 2026-03-20


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