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Information × Registration Number 0213U000141, 0112U003142 , R & D reports Title Development of technologies of synthesis and creation of pure coordination compounds based on biologically active complexones for using as diagnostic materials in biomedical popup.stage_title Head Trunova Olena Kostjantynivna, Registration Date 18-01-2013 Organization V.I.Vernadskii Institute of General and Inorganic Chemistry NASU popup.description2 Refined the method of synthesis and synthesized lanthanide (Gd and Dysprosium) with complexones (ethylenediaminedisuccinic, диетилентриамінпентаоцтовою and oksietilidendyfosfonovoyu acids) The composition and structure the synthesized compounds in solution and solid state, established their basic physical and chemical characteristics. Physico-chemical methods, it is shown that f-coordinate metal atoms of nitrogen and three atoms of oxygen and alfa and beta-carboxyl groups of the molecule ethylenediaminedisuccinic acid and the oxygen atoms of alcogol and phosphonic groups. Studied the spectral-luminescent properties of the synthesized compounds. For all gadolinium complexes detected luminescence of Gd(III) ions in the UV region in solution, both in solid samples. A toxicological study. Found that all the compounds are low-toxic substances with poorly pronounced irritant effect with no skin-resorptive and cumulative properties. A toxicological passport was designed. Product Description popup.authors Бережницька Олександра Степанівна Гудима Андрій Олегович Макотрик Тамара Олексіївна Роговцов Олександр Олександрович Федорів Ярослав Віталійович Шовкова Ганна Василівна popup.nrat_date 2020-04-02 Close