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Information × Registration Number 0213U000162, 0112U002411 , R & D reports Title To investigate biochemical ground of changes of endocrine regulation of bone structures in children with the acute leukemia, which were exposed to ionizing radiation due to the Chernobyl accident popup.stage_title Head Bruslova Ekaterina Mihailovna, Registration Date 18-01-2013 Organization State institution "National research centеr for radiation medicine of the National academy of medical sciences of Ukraine " popup.description2 Object of research: 259 children (53 patients with acute leukemias, 206 persons of control group). Aim: to study indicators of endocrine regulation of bone structures at patients with leukemias which have undergone impact of ionizing radiation due to accident in Chernobyl NPP, and to estimate the course of disease in dynamics of leukemic process. Research methods: clinical, immunological, biochemical, cultural, biophysical, mathematical. Levels of glucocorticoids, thyroid gland and hypophysis hormones at children with acute leukemias are studied and the course of leukemias in dynamics in virue of endocrine indicators, urine aminoacids composition , bone degradation markers, acid-alkaline balance, efficiency of bone marrow fibroblasts colony-forming ability and bone density assessment is estimated. Product Description popup.authors Ільєнко І.М. Базика Д.А. Володіна Т.Т. Емчинський Є.В. Кузнєцова О.Є. Ляшенко Л.О. Мазурик Н.Я. Пушкарьова Т.І. Самсон Ю.М. Цвєткова Н.М. popup.nrat_date 2020-04-02 Close