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Information × Registration Number 0213U000539, 0110U002205 , R & D reports Title To develop and to advance extended, combined and reconstructive plastic operations, directed on increasing treatment efficiency and improvement of life quality of patients with malignant head and neck tumor. popup.stage_title Head Protsyk Volodimir, Registration Date 14-02-2013 Organization Ukrainian Research Institute of Oncology and Radiology popup.description2 The object of study - 315 head and neck cancer patients. Purpose - to increase the effectiveness of treatment and quality of life in patients with malignant tumors of the head and neck through the development and improvement of advanced, combined and reconstructive plastic surgery. Methods: clinical, clinical laboratory, radiological, pathological, and statistical. Results. Developed working classification of postoperative defects of the head and neck, including the location and size of resection provides the opportunity to plan the reconstruction of a varied selection of the optimal graft. Found that the most effective way to restore large oropharyngeal postoperative defects, skin and soft tissues of the face and neck defects is the pectoralis major myocutaneous flap reconstruction on vascular pedicle. Developed and implemented a new method of plastic reconstructive total lower lip defects by using tissues of chin and submental area can reduce the invasiveness of surgery and provides good functional and cosmetic results. The results showed that the developed methods of reconstruction oropharyngeal defects with vascularized tissue complexes improved the quality of life of patients (30.9 - 47.7%) comparing to traditional methods of plastics. Extended and combined surgery with simultaneous large postoperative defects reconstruction with vascularized tissue complexes increased on 13.3% two-year survival oropharyngeal cancer patients comparing with the postoperative defects plastic using local tissues. Product Description popup.authors Коробко Євген Володимирович Петренко Людмила Іванівна Руденко Дмитро Миколайович popup.nrat_date 2020-04-02 Close