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Information × Registration Number 0213U000653, 0112U000017 , R & D reports Title To develop the methods of the treatment for patients with malignant tumors of the abdomen popup.stage_title Head Shchepotin Igor Borysovich, Registration Date 01-03-2013 Organization Ukrainian Research Institute of Oncology and Radiology popup.description2 The technique of the D3 - lymphodissection in patients with gastric cancer were studied in a randomized trial ( D2 vs + D3). These outcomes suggest that the technique does not increase blood loss, significantly prolongs the operation does not increase the number of postoperative complications. The analysis of the results of combined treatment of patients with gastric cancer using neoadjuvant chemotherapy. The use of neoadjuvant chemotherapy (PELF regimen) is safe, not accompanied by significant toxic manifestations and does not increase the number of postoperative complications. Proved high sensitivity and specificity markers p53, bcl-2, VGEF in patients with gastric cancer. Determination of sensitivity to chemotherapy allowed to individualize treatment for patients with cancer of the stomach, increase the number of partial regression in 2,5-3 times. Developed and applied multimodal program Fast track surgery for patients with pancreatic cancer. Randomized trial found that the use of FTS program increases the effectiveness of surgical treatment as a means to reduce postoperative complications, accelerate term rehabilitation.The technique FTS for patients with pancreatic cancer has established itself as safe, with the prospect of shortening the operation time of 1.3 times intraoperative blood loss and the percentage delay evacuation from the stomach by 25%. The technique combined surgery with removal of malignant tumors of the retroperitoneum, with resection and / or extirpation surrounding organs or structures and total removal of retroperitoneal fat. A comparative analysis of developed technique combined surgery and isolated tumor removal in patients with malignant tumors of the retroperitoneum. Studied results of combined treatment of patients with locally advanced rectal cancer using neoadjuvant radiotherapy (2 Gy x 20) and different chemotherapy regimens. The majority of patients in both groups reported an objective response to therapy as partial regression and stabilization. Tumor regression was more significant in patients using capecitabine and oxaliplatin. Combined treatment of patients with locally advanced rectal cancer with chemotherapy is safe, promotes tumor regression, provides an opportunity to increase the number of sphincter-preserving operations and improve the quality of life of patients. Product Description popup.authors Жуков Юрій Олександрович Колеснік Олена Олександрівна Лукашенко Андрій Володимирович Розумій Дмитро Олександрович popup.nrat_date 2020-04-02 Close