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Information × Registration Number 0213U001196, 0109U008670 , R & D reports Title The dinamic disturbance of coagulative and fibrinolitic systems in development of commissural diseases in abdominal cavity popup.stage_title Head Todurov I.M., Registration Date 23-01-2013 Organization National institute of surgery and transplantology named after Shalimov O.O. of the Academy of Medical Sciences of Ukraine popup.description2 While studying the theme, condition coagulation and fibrinolytic systems of blood, the quantitative determination of their main components, interleukins and blood lipids had been researched. Also, there was investigated microflora intestines and abdominal cavity. It was found, the correlation presence between the process of formation of postoperative adhesions in the abdominal cavity and increasing levels of plasminogen activator inhibitor and decreasing levels of tissue plasminogen activator 3-5 more times relative to normal, the presence of high concentrations of soluble fibrin values-monomer complexes and D-dimer levels in the serum of patients with adhesive disease, which may be as a marker of high risk of thrombosis and / or adverse flow of adhesive disease. The level of proinflammatory cytokines had been increased till 6-9 day in patients with peritoneal adhesive disease, but in patients without clinical signs of disease level of proinflammatory cytokines had been reduced. We propose a mathematic model of predicting of abdominal adhesive disease in surgical patients based on calculating of the coagulation system. Product Description popup.authors Дєєв Валерій Аркадійович Дашенко Наталія Петрівна Калашніков Олександр Олександрович Куповська Світлана Іванівна Лисак Любов Іванівна Осипенко Катерина Петрівна Смітюх Людмила Анатоліївна Швадчин Ігор Олександрович popup.nrat_date 2020-04-02 Close