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0213U001968,
0111U009944
,
Developing new ways to heterokondensed systems and directed synthesis of compounds with anticancer properties based on them
Popov Anatolij Fedorovich, Доктор хімічних наук
18-03-2013
The L.M.Litvinenko Institute of Physical-Organic Chemistry and Coal Chemistry
Object of study - functionalized pyrazolo [3,4-c] isoquinoline, methods for their preparation in view of their biological activity, aim - to explore methods of obtaining and structural and physical properties himichyyh functionalized by heterocyclic nuclei pyrazolo [3,4-c] isoquinoline; Methods - organic synthesis, NMR, IR spectroscopy, thin layer, high performance liquid chromatography and volume, QSAR analysis, theoretical and practical - the first time the methods of general functionalization pyrazolo [3,4-c] isoquinoline in heterocyclic nuclei , met odes QSAR highlighted the most promising areas of modification structures for their anticancer properties, prepared according substituted derivatives of pyrazolo [3,4-c] isoquinoline for biological screening and finding effective anticancer kinase inhibitors with low toxicity
Абрамянц Маргарита Григорівна
Білобров Володимир Мокієвич
Богдан Наталя Михайлівна
Богза Сергій Леонідович
Дмитрук Олександр Філаретович
Зінченко Софія Юрієвна
Заречна Ольга Миколаївна
Кібальний Олександр Володимирович
Каніболоцький Олександр Володимирович
Ломов Дмитро Олександрович
Пендюх В'ячеслав Володимирович
Перепічка Дмитро Федорович
Суйков Сергій Юрійович
Толкунов Андрій Сергійович
Толкунов Валерій Сергійович
Толкунов Сергій Володимирович
Тюрина Тетяна Григорівна
Хабаров Костянтин Михайлович
Хижан Олександр Іванович
2020-04-02
Updated: 2025-12-07
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