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Information × Registration Number 0213U002049, 0112U002656 , R & D reports Title Development of method for synthesis of chiral organophosphorus compounds with potential biological activity. popup.stage_title Head Kolodyazny O., Доктор хімічних наук Registration Date 10-01-2013 Organization Institute of Bioorganic Chemistry and Petrochemistry of National Academy of Sciences of Ukraine popup.description2 Methods for biocatalytic separation of alpha and beta-hydroxyphosphonates by Burkholderіa cepacіa lipase were developed. New organocatalysts on the basis of L-Tyrosine and its derivatives capable to catalyze the aldol reactions in hydroxylcontaining medium, including water solutions, were developed The method of enzymatic resolution of racemic compounds to enatiomerers by acylation of secondary alcohols with cyclic anhydrides of dicarbonic acids was developed. All possible stereoisomers of cis- and trance-vicinal cyclic alkenes (n=4-6) which are chiral synthons for the preparation of leucotrienes and prostaglandins were synthesized Product Description popup.authors А.О.Колодяжна Гришкун Е В С М Шейко popup.nrat_date 2020-04-02 Close