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Information × Registration Number 0213U002101, 0112U003691 , R & D reports Title Development of methodology for obtaining, operating time prototype and preclinical study of generic drug 'Letrozole'. SECTION1. Development of methodology for obtaining and working prototypes of generic drug letrozole popup.stage_title Head Bogza Sergij Leonidovych, Доктор хімічних наук Registration Date 15-01-2013 Organization The L.M.Litvinenko Institute of Physical-Organic Chemistry and Coal Chemistry popup.description2 Object of study - patent information, synthetic methods for generic drug Letrozole. The aim - to develop methods of producing generic Letrozole suitable for implementation in the Ukrainian pharmaceutical manufacture and generation prototype for preclinical trials. Methods - organic synthesis, NMR, IR spectroscopy, thin layer, high performance liquid chromatography and volume; theoretical and practical - the rational synthesis of drug trends, the key output connections that need to target industrial process. The simulation of the main reactions and processes for the synthesis of the drug Letrozole. The possibility of a drug in the existing process conditions with acceptable yields and satisfactory quality. Product Description popup.authors Богдан Наталя Михайлівна Бондаренко Олександр Вікторович Зінченко Софія Юрієвна Пендюх Вячеслав Володимирович Суйков Сергій Юрійович popup.nrat_date 2020-04-02 Close