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Information × Registration Number 0213U002102, 0112U003692 , R & D reports Title Developement of anticancer heterocondensed isoquinolines library popup.stage_title Head Popov Anatolij Fedorovich, Доктор хімічних наук Registration Date 15-01-2013 Organization The L.M.Litvinenko Institute of Physical-Organic Chemistry and Coal Chemistry popup.description2 Research object - functionalized 4-aryl-5-aminopyrazoles, methodes for synthesis and cyclizations, functionalized pyrazolo[3,4-c]isoquinolines; Main scope - to develope synthesis, investigation there structural, spectral and analytical data and cyclizations of 4-aryl-5-aminopyrazoles; Research methods - organic synthesis, NMR-, IR-spectroscopy, TL-, HPL- and coloumn chromatograhpy; Theoretical and practice results - at firstly was developed synthetic methods for synthesis 4-aryl-5-aminopyrazoles with amino-, carboxy- and carboxyakyl groups in heterocyclic core, on these base was obtained pyrazolo[3,4-c]isoquinoline derivatives for bioligical scrining and search for a new low-toxic anticancer kinaze inhibitors. Product Description popup.authors Богдан Наталя Михайлівна Богза Сергій Леонідович Зінченко Софія Юрієвна Пендюх Вячеслав Володимирович Сизоненко Олена Сергіївна Суйков Сергій Юрійович Хижан Олександр Іванович popup.nrat_date 2020-04-02 Close