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Information × Registration Number 0213U002458, 0112U008216 , R & D reports Title Development of luminescent marking method of liposomal nanocontainers for diagnosis of their interaction with living cells. popup.stage_title Head Yefimova S.L., Registration Date 29-01-2013 Organization Scientific-research department of alkali halide crystals with experimental manufacture STC "Institute for single crystals" NAS of Ukraine popup.description2 The work contains the study of occurrence of the non-radiating fluorescence resonance energy transfer (FRET) among several organic pigments, which are incorporated in the liposome. Grounding on the executed studies, there was developed the luminescent marking method of the liposome nanocontainers, based on the FRET occurrence and its dependence on the distance between the molecules of donor and acceptor of the electronic excitation energy. There was studied the influence of molecules structure and nanocontainer size on the efficiency of FRET in couples of pigments. It was shown that when creating the compositions with non-radiating fluorescence resonance energy transfer in the nanovolume it is important to consider the capability of molecules to interact among themselves: a tendency to formation of dimers and more complicated aggregates, formation of specific complexes at the expense of Coulomb and van der Waals interactions, steric obstacles. Product Description popup.authors Клочков В.К. Сорокін О.В. popup.nrat_date 2020-04-02 Close