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Information × Registration Number 0213U002690, 0110U002253 , R & D reports Title To develop new colloid plasma-like solutions with polyfunctional effect and solution for blood conservation and erythrocytes resuspendation (laboratory experimental and clinical research) popup.stage_title Head Kondratskyi Bogdan O., Novak Vasyl' L., Registration Date 04-02-2013 Organization LVIV RESEARCH INSTITUTE OF BLOOD PATHOLOGY AND TRANSFUSIONAL MEDICINE popup.description2 The results of the development of manufacturing technology and quality control of a new infusion solution HAES-LX-5% are presented. Found that for white mice and white rats the average lethal dose LD50 is greater than 180 ml/kg body weight. The use of HAES-LX-5% in rats with burn shock shown that seven-day infusion therapy prevents development of destructive changes in hepatocytes, promotes restoration of disturbed bioenergetic processes in the liver, promotes conservation pool of antioxidant enzymes and inhibits lipid peroxidation and oxidative modification of protein. Presented results of the combined infusion therapy with drugs Xylat and Lactoprotein with sorbitol in the treatment of 36 patients with chronic alcoholic hepatitis with minimal activity, use of drugs and Rheosorbilact and Xylat in treatment of 100 patients with diffused phlegmons of the maxillofacial area, and application of Rheosorbilact in complex treatment of 35 cancer patients after resection of the esophagus in the early postoperative period. Developed the technology of production and control of a new protein-saline solution ALX-5% on the basis of albumin, xylitol, sodium lactate and electrolytes. Product Description popup.authors Івасик Віктор Володимирович Брагінець Олена Григорівна Винарчик Марія Йосипівна Волос Ольга Петрівна Городиська Олена Олександрівна Деркач Юлія Володимирівна Дзісь Роман Петрович Дорошенко Людмила Григорівна Захарків Любов Іванівна Качмарик Діана Любомирівна Кокоруз Мар'яна Володимирівна Кондрацький Ярослав Богданович Медвідь Юлія Олегівна Новосад Анна Богданівна Орчинська Зоряна Володимирівна Панас Оксана Михайлівна Рогатинська Ярослава Василівна Семененко Андрій Ігорович Тушницький Орест Миронович popup.nrat_date 2020-04-02 Close
R & D report
Head: Kondratskyi Bogdan O., Novak Vasyl' L.. To develop new colloid plasma-like solutions with polyfunctional effect and solution for blood conservation and erythrocytes resuspendation (laboratory experimental and clinical research). (popup.stage: ). LVIV RESEARCH INSTITUTE OF BLOOD PATHOLOGY AND TRANSFUSIONAL MEDICINE. № 0213U002690
1 documents found

Updated: 2026-03-24