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Information × Registration Number 0213U003133, 0110U005317 , R & D reports Title New biochemical approaches for evaluation of ecotoxicity of metallic nanoparticles based on determination of metallothioneins characteristics in water animals popup.stage_title Head Stoika Rostyslav, Registration Date 24-01-2013 Organization Institute of cell biology, National Academy of Sciences of Ukraine popup.description2 Multimarker (more than 30 parameters) molecular analysis of the functional state of the frog Rana ridibunda was implemented and the role of the metal-depositing proteins metallothioneins (MT) in response of the body to the action of cobalt-and zinc-containing nanomaterials (Co-Zn-HC and HC) and their components was explained. Comparison of studies results of biomarkers bivalve mollusc Anodonta cygnea, silver crucian carp Carassius auratus gibelio and lake frog Rana ridibunda shows phylogenetically-determined differences in the efficiency of biotransformation in metabolically active tissues and sensitivity of quantitative characteristics of metallothioneins to reflect this difference that creates objective conditions for evaluation ecotoxicity of metal-containing nanomaterials on the basis of metallothioneins characterization of aquatic animals. Product Description popup.authors Корчинський Олександр Геннадійович Стойка Ростислав Степанович Столяр Оксана Борисівна Фальфушинська Галина Іванівна popup.nrat_date 2020-04-02 Close