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Information × Registration Number 0213U003652, 0110U001218 , R & D reports Title Study the mechanism of pharmacological effects of physiologically active compounds and drugs analgesic action under modification antioxidant-prooxidant system cells popup.stage_title Head Gubskiy Yuri Ivanovich, Buhtiarova Tatiana Anatolievna, Registration Date 28-02-2013 Organization State Establishment "Institute of Pharmacology and Toxicology National Academy of Medical Science of Ukraine" popup.description2 The effect of antioxidants and non-narcotic analgesics on the structural and dynamic parameters of erythrocyte membranes was in acute pain. It is shown that the introduction of an animal with a sharp pain narcotic analgesics - ketorolac and ketorolac combination of tocopherol helps to normalize the parameters describing the structure of the protein and lipid-protein distance in erythrocyte membranes. It is shown that in the acute pain of ketorolac, alpha-tocopherol and their combination leads to a decrease in lipid peroxidation in erythrocyte membranes of rats and increased osmotic resistance of the erythrocyte membrane. Product Description popup.authors Бабенко Л.П. Бершова Т.А. Бобкова Л.С. Горюшко Г.Г. Демченко А.М. Кокоша О.В. Курапова Т.М. Літвінова Н.В. Хоменко В.С. Ядловський О.Є. popup.nrat_date 2020-04-02 Close