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Information × Registration Number 0213U003923, 0109U007153 , R & D reports Title The development and approbation of nanotechnological approaches to tumor photodynamic therapy effectiveness increase popup.stage_title Head Gamaleia Nikolay Fedorovich, Registration Date 07-02-2013 Organization R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology popup.description2 Porphyrin-based composites of photosensitizers hematoporphyrin, chlorin e6 and Fotolon with nanoscale colloidal gold were created. Enhancement in photodynamic activity of porphyrin-based nanogold compositions was demonstrated in experiments with model solutions, human malignant lymphocytes in vitro and transplanted tumors in vivo. Lifespan of Lewis lung carcinoma bearing mice that received photodynamic treatment with Fotolon-gold nanocomposite 4,5 times exceeded lifespan of untreated mice and 2 times exceeded lifespan of mice photodynamically treated with Fotolon only. Product Description popup.authors Гамалія Микола Федорович Долинський Геннадій Анатолійович Завадська Тетяна Станіславівна Прокопенко Ігор Вікторович Шишко Євгенія Денисівна popup.nrat_date 2020-04-02 Close