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Information × Registration Number 0213U004070, 0110U001174 , R & D reports Title To investigate a process of formation the states of different dependence (tobacco smoking, alcoholism, drug addition, gambling) popup.stage_title Head Linsky I. V., Minko A. I., Registration Date 31-01-2013 Organization State Institution " Institute neurology, psychiatry and narcology AMS of Ukraine" popup.description2 Object of investigation - mechanisms of inheritance of predisposition to conditions of dependence of different origin. The work purpose - to study mechanisms of inheritance of predisposition to conditions of dependence of different origin (a tobacco smoking, alcoholism, drug addiction, gambling, etc.). And mechanisms of its realization under the influence of environment and on this basis to develop new approaches concerning preventive maintenance and therapy. Research methods - system of AUDIT-like tests for a complex estimation addictive status; a questionnaire for definition of addiction severity index; methods of mathematical statistics. Results. The representative cohort of patients of a narcological profile is created. Social, legal, family, demographic, medical and addictive features of members of the specified cohort are analyzed. The phenomenon of accumulation of cases of a tobacco smoking and drunkenness in families of the patients amazed with disorders of a narcological profile is described. It is proved, that the genetic component of inheritance of predisposition to conditions of dependence of a different origin is realized on the additive mechanism by group concerning the genes equal in rights, any of which does not dominate over others, and level of the specified predisposition is defined by "dose" of the specified genes which has received probands. Product Description popup.authors Артемчук А. Артемчук К. Бараненко О. Виглазова О. Гайдабрус А. Гегешко В. Гема О. Гольцова С. Лінський І. Лісна Н. Мінко О. Мінко О. Маркозова Л. Мусієнко Г. Самойлова О. Сергієнко О Серьогіна В. Шалашов В. Юрченко О. popup.nrat_date 2020-04-02 Close