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Information × Registration Number 0213U004481, 0112U002927 , R & D reports Title Development and creation of high effective antimicrobial agents based on metal nanoparticles and their conjugates with antibiotics for nosocomial infections treatment popup.stage_title Head Ulberg Zoja Rudolfovna, Registration Date 20-12-2013 Organization F.D. Ovcharenko Institute of biocolloidal Chemistry NAS of Ukraine popup.description2 Original protocols for metal (gold, silver, copper, bismuth) nanoparticles' synthesis as well as their conjugates with different pharmacological substances by the methods of colloidal-chemical reduction in water medium have been developed. All metal nanoparticles and their conjugates have been characterized according to the criterions of biosafety and biocompatibility. The metal nanoparticles' high bactericidal and fungicidal activity according to the wide spectrum of resistant and multiple- resistant clinical isolates - causative agents of nosocomial infections have been determined in vitro and in vivo. Product Description popup.authors Грузіна Тамара Григоровна Дибкова Світлана Миколаївна Рєзніченко Людмила Сергіївна popup.nrat_date 2020-04-02 Close