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Information × Registration Number 0213U004650, 0111U000614 , R & D reports Title Development of algorithm of prophilaxis of viral infections (HIV-infections/AIDS, hepatitis B,C) transmissible hematransfusion by a way at the use of components and preparations of donor blood popup.stage_title Head Perechrestenko P.M., Registration Date 20-12-2013 Organization Kiev Research Institute of Haematolojy and Blood Transfusion popup.description2 Object of research - the samples of blood serum of donors (7595), recipients of multiple transfusions (49), immunoglobulins different specific focus (30). The purpose of work is based on the study of proliferation markers of pathogens viral infections optimize measures for the confiscation of media virus (HIV1/2, hepatitis В, C) with donor contingent to achieve a high degree of viral blood transfusions and develop an algorithm for the prevention of HIV and viral hepatites В and C, which are transmitted by blood transfusion. Research methods: enzyme-linked immunosorbent assay, polymerase chain reaction. Results: in 7595 donors and 49 multiple recipients of blood transfusions 30 samples of immunoglobulins of different specific focus was conducted 23180 research by ELISA blood serum for the presence of markers of HIV1/2, HCV, HBV, detection of nucleic acids relevant viruses in 60 samples of blood serum of inconclusive for ELISA. Samples are distributed on the positive (108), negative (22356) and null (4,29%). Further research was conducted by ELISA using test systems for determination of the cross-reacting antibodies and nucleic acids by PCR. In 3 samples detected HIV RNA in number, indicating an early seroconversion and 3 samples with nucleic acids virus, hepatitis В and C, respectively; 100% of the samples contain cross-reacting antibody. On the basis of the results obtained developed algorithm to prevent HIV infection and viral hepatitis В and C, which are transmitted by blood transfusion. Medico-social effect. Medicine. Product Description popup.authors Авер,янов Є.В. Захаренко О.С. О.О. Федоровська Павлюк Р.П. Тимошенко У.В. popup.nrat_date 2020-04-02 Close