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Information × Registration Number 0213U004823, 0113U005313 , R & D reports Title Molecular mechanisms of antidiabetic effect of drugs from plant origin popup.stage_title Head Sybirna Nataliya Oleksandrivna, Registration Date 27-12-2013 Organization Ivan Franko National University of Lviv popup.description2 Is dedicated to the investigation the hypoglycemic effect of nonalkaloid Galega officinalis extract and Anthocyanidin of red cabbage influence on the structural and functional state of the rats peripheral blood cells under experimental diabetes mellitus type 1. Administration of Galega officinalis extract and Anthocyanidin of red cabbage at a dose of 0.6 g per 1 kg of animal per os reveals the marked hypoglycemic effect under the diabetes mellitus condition, corrective influence on the erythron indicators (the decrease of quantity and daily production of reticulocytes, ratio normalization of erythrocyte populations of different ages, their resistance to hemolytic increase). Study the composition of Galega officinalis extract chloroform fraction has been performed by the method of chromatography-mass spectrometry. In the current study was revealed 29 compounds from which were identifi ed fatty acids and their esters, diterpenes, triterpenes, phytosterols and fl avanoids. The prevailing content of palmitic acid ethyl ester and linolenic acid methyl ester in the chloroform fraction has been established. Hypoglycemic effect of the test extract may be due to the presence phytol, palmitic acid ethyl ester, phytosterols (campesterol and stigmasterol) and а-amyrin. Product Description popup.authors Канюка Олена Петрівна Клевета Галина Ярославівна Лупак Маряна Ігорівна Сибірна Наталія Олександрівна popup.nrat_date 2020-04-02 Close