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Information × Registration Number 0213U005264, 0110U003642 , R & D reports Title Investigetion fo methods internal organs injuring correction of medical and other genesis popup.stage_title Head Posokhova Kateryna Andriyvna, Доктор медичних наук Registration Date 02-04-2013 Organization Ternopol State Medical University by I.Ya.Horbachevsky popup.description2 A study of the influence of modulators of nitric oxide synthesis on the functional state of the liver and biliary excretion processes in acute toxic hepatitis, cholestatic liver damage. Established the positive effects of L-arginine and L-arginine-L-glutamate. The pathogenesis of liver injury in acute paracetamol poisoning was studied. It was found the higher hepatoprotective activity of thiotriazolin compared with acetylcysteine, which is confirmed by a significant decreasing of marker enzymes of cytolysis and cholestasis, decreasing of indices of lipid peroxidation, normalization of antioxidants activity and restoring of energy processes in the liver mitochondrias. L-ARGININE, L-ARGININE-L-GLUTAMATE, N-NITRO-L-ARGININE, АMINOGUANIDINE, MELATONINE,LIVER, ACUTE TOXIC LIVER INJURY, CIRRHOSIS, ISCHEMIA-REPERFUSION LIVER, ACUTE PARACETAMOL LESIONS, ТHIOTRIASOLIN, АCETYLCYSTEINE, АNTIOXIDANT SYSTEM Product Description popup.authors Вольська А.С. Олещук О.М. popup.nrat_date 2020-04-02 Close