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Information × Registration Number 0213U005389, 0111U007663 , R & D reports Title Peptides and proteins as targets of drugs, the synthesis of self-assembled molecular capsules - research and development of new technologies. popup.stage_title Head Komarov Igor, Registration Date 17-05-2013 Organization Taras Shevchenko Kiev university popup.description2 he synthesis model (known) short-chain peptides. Synthesized building block containing fotoperemykach - molecular fragment that can change its conformation oborotno by light. Synthesized peptides based on it. These peptides are constructed on the basis of known compounds that exhibit antimicrobial properties and fluorinated analogs of the above peptides for their studies in membranes by 19F-NMR. We found that the "switch" peptide response to light at different wavelengths effective at known physical properties of membranes and antimicrobial activity. Membranopronyknyy synthesized peptide, SAP, and its fluorinated analogues. Studied the formation of complexes of peptides with nanoparticles and penetration of these complexes into eukaryotic cells. The phenomenon of transport of nanoparticles into cells mediated by the interaction of the peptide SAP. Product Description popup.authors Комаров І. Радченко Д. Рачков О. Рожков В. Шиванюк О. popup.nrat_date 2020-04-02 Close