Search academic texts

Information × Registration Number 0213U006661, 0112U004262 , R & D reports Title Molecular design, synthesis and biological studies of calixarene regulators of intracellular calcium homeostasis in smooth muscle in normal state and in contractile function disruption. popup.stage_title Head Kalchenko Vitaliy Ivanovich, Доктор хімічних наук Registration Date 23-12-2013 Organization Institute of Organic Chemistry National Academy of Sciences of the Ukraine popup.description2 The object of research is new calixarenes modified pharmacophoric sulfonilamidine and phosphonate groups. Objective - development of methods for the synthesis of such compounds, the study of their spatial structure and properties, as well as conducting comprehensive studies of influence these calixarenes on the systems of active transport of Ca2+ and Na2+ cations. As a result of the project the new selective circulating effectors of transport Ca2+,Mg2+-ATPase and Na+,K+- ATPase of plasma membrane were received. The results can be used in physical, chemical and medical research, and biochemistry. Product Description popup.authors Єсипенко Олександр Адольфович Бойко Вячеслав Іванович Драпайло Андрій Богданович Кальченко Віталій Іванович Карпусь Андрій Олегович Поліщук Кирило Анатолійович Родік Роман Васильович Харченко Сергій Григорович Хоменко Андрій Володимирович Черенок Сергій Олексійович popup.nrat_date 2020-04-02 Close