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Information × Registration Number 0213U006687, 0113U007229 , R & D reports Title Novel oligomeric carriers and nanosized systems of targeted drug delivery popup.stage_title Head Taras Skorokhoda, Registration Date 24-12-2013 Organization Lviv Polytechnic National University popup.description2 Surface active comb-like polymers and gels with polyethylene glycol and polyelectrolyte chains were synthesized by radical copolymerization reactions and polymer-analog transformations of oligomers with peroxide and epoxy fragments. Multifunctional nanocomposites of lanthanum phosphate were obtained and the possibility of their use as biologically inert markers in cancer cells was shown. A nanoscale oligomeric systems with doxorubicin were formed; in vitro and in vivo investigations revealed that carriers and delivery systems of doxorubicin are non-toxic and provide a cardioprotective effect against doxorubicin action, accelerate the delivery of drugs into cells, reducing the therapeutic dose and overcome acquired resistance of cells to drugs. Product Description popup.authors Дзяман Ірина Зіновіївна Дудок Галина Дмитрівна Москвін Максим Максимович Мягкота Олеся Степанівна Навроцький Святослав Богданович Половкович Святослав Володимирович Рябцева Анна Олександрівна Сеньків Юлія Василівна Скорохода Тарас Володимирович Шаповал Олександр Володимирович popup.nrat_date 2020-04-02 Close