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Information × Registration Number 0213U006774, 0113U005317 , R & D reports Title Development of electrochemical and photochemical biosensors with using membranes based on chloroplasts and enzymes popup.stage_title Head Soldatkin Alexey, Доктор біологічних наук Registration Date 30-12-2013 Organization Institute of Molecular Biology and Genetics of NASU popup.description2 A conductometric biosensor based on immobilized acetylcholinesterase and his laboratory prototype were developed. Activity of biosensor was tested according to responses to the substrate acetylcholine. At the next step sensitivity of the biosensor was evaluated to various toxic substances, the major environmental pollutants and food toxicants (glycoalkaloids and neurotoxins, reversible inhibitor of acetylcholinesterase, organophosphorus pesticides and heavy metal ions as irreversible inhibitors of acetylcholinesterase), and investigated the possibility of regeneration of enzyme activity with specific reagents (reactivators). Possibility of regulating the sensitivity and selectivity of the biosensor and the possibility of repeated use of biosensors for inhibitor analysis of toxicants was demonstrated. Product Description popup.authors Дзядевич С.В Пєшкова В.М. Солдаткін О.О. popup.nrat_date 2020-04-02 Close