Search academic texts

Information × Registration Number 0213U006897, 0110U005552 , R & D reports Title Investigation of tumor microenvironment modifying effect on magnetization, dispersity, biocompatibility and stability of magnetic fluids on the basis of complex ferromagnetic oxides popup.stage_title Head Osynsky Sergy Petrovych, Registration Date 10-01-2014 Organization R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology popup.description2 Magnetic fluids (MF) on the basis of ferromagnetic materials with spinel structure (magnetit) and perovskite (manganste) were syntesized. It was shown that heating of magnetit MF under action of alternating magnetic field (AMF) is depended on pH of micromilieu and pH of MF. Manganite MF does not demonstrate pH dependence. Tumor reaction after MF administration into the tumor is characterized by stromal element activation. Distribution of nanoparticles through out tumor is not homogenous. Nanoparticles are absent in normal tissues. It is reasoned to provide the preclinical studies of manganite MF Product Description popup.authors Бубновська Лариса Микитівна Гуменюк Ліля Дмитрівна Клепець Леонід Феодосійович Ковельська Антоніна Василівна Мамонтова Леся Анатолієвна Михайленко Віктор Михайлович Осинський Сергій Петрович popup.nrat_date 2020-04-02 Close