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Information × Registration Number 0213U007435, 0110U003032 , R & D reports Title Investigation of genetic peculiarities of allergic inflammation development and target-organs formation popup.stage_title Head Kaidashev Igor Petrovich, Registration Date 31-10-2013 Organization The Higher State Educational Establishment of Ukraine "Ukrainian Medical Stomatological Academy". popup.description2 The levels of allergen-specific IgE in allergic patients of Poltava region were analyzed. The data which indicates that the most significant and causal allergens in the development of allergic diseases in Poltava population are epidermal allergens, D. pteronyssinus, and D. farinae. The prevalence of gene polymorphisms of matrix metalloproteinase-12 A-82G and methylenetetrahydrofolate reductase Ala222Val (C677T) was examined for the first time. The absence of homozygous variant of GG genotype for mutant allele was observed. Determination of elastin gene polymorphism g28179 A> G in exon 20 in patients with hernias. The data on the prevalence of this polymorphism in patients with hernia disease was obtained for the first time in Ukraine. The role of allel polymorphism of l-myc and P53 genes in the development of endometrial hyperplastic processes was examined. Polymorphism of p53 and l-myc genes may contribute to the atypical transformation of cells in proliferatively changed endometrial. Product Description popup.authors Ізмайлова Ольга Віталіївна Боброва Нелля Олександрівна Весніна Людмила Едуардівна Куценко Неля Леонідівна Левченко Лілія Юріївна Ляховська Наталья Вячеславівна Микитюк Марина Володимирівна Сакевич Вікторія Дмитрівна Шликова Оксана Анатоліївна popup.nrat_date 2020-04-02 Close