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Information × Registration Number 0213U007566, 0113U002984 , R & D reports Title Multicomponent reactions in the synthesis of nitrogen containing heterocycles with pharmacophore fragments popup.stage_title Head Mykola Dmytrovych Obushak, Registration Date 23-12-2013 Organization Ivan Franko National University of Lviv popup.description2 The new approaches to the arylation of the furan and thiophene derivatives were developed. 5-Arylthiophene(furan)-2-carbaldehydes and 1,3-diarylpyrazole-4-carboldehydes were synthesized. The reaction of arenediazonium salts with ethyl 2-methylacetoacetone and ethyl 2-chloroacetoacetone were investigated. Cyclizations of substituted 1,4-dicarbonyl compounds with formation of carbonyl containing arylfuran(thiophenes) were studied. 1-Aryl-4-formyl/4-acetyl-5-methyl-1H-pyrazole-3-carboxylates were obtained. Product Description popup.authors Горак Юрій Ігорович Литвин Роман Зіновійович popup.nrat_date 2020-04-02 Close