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Information × Registration Number 0213U007728, 0111U007663 , R & D reports Title Peptides and proteins as targets of drugs, the synthesis of self-assembled molecular capsules - research and development of new technologies. popup.stage_title Head Komarov Igor, Registration Date 17-06-2013 Organization Taras Shevchenko Kiev university popup.description2 Synthesized short cyclic peptides containing six amino acids - known analogues of cyclic antimicrobial peptide c-(WFW). One or three amino acid residues in the c-(WFW) to be replaced in the analogues conformationally hindered amino acids to improve the selectivity of antimicrobial action. It is shown that analogues have the same antimicrobial activity as the peptide-prototype s-(WFW). Analogs are characterized by the ability to effectively inhibit the growth of bacterial colonies - can destroy biofilms and biofilm at sufficiently low concentrations. We found that the antibiotic peptide analogs of natural gramicidin S with fotoperemykachem within the polypeptide chain change their biological activity oborotno by light. Manage aktyvnstyu antibiotics by light can be the basis of new technologies treatment of infectious diseases. Product Description popup.authors Комаров І. Коновець А. Радченко Д. Рожков В. Шиванюк О. popup.nrat_date 2020-04-02 Close