Search academic texts

Information × Registration Number 0213U008303, 0111U001368 , R & D reports Title Determination of the additional risk of unfavourable events developmentin patients with different forms of ischemic heart disease at the basis of activity and genetical polymorphism of protease-antiprotease system studying. popup.stage_title Head Dzyak Georgy Victorovich, Registration Date 13-01-2014 Organization State organization "Dnepropetrovsk medikal akademy of Ministry Health Ukraine" popup.description2 Based on the definition of indicators protease antiproteaznoy system installed additional criteria for predicting the course of coronary heart disease and monitoring the effectiveness of therapeutic interventions. Proved that no fragments of fibronectin (FFN) 60-72 and 75-80 kDa in all terms of hospital and post-hospital period and the presence of FFN 165-175 kDa is a typical indicator of acute coronary syndrome without ST-segment elevation with the formation of an acute myocardial infarction without tooth Q. The ratio of active MMP-9 in the coronary and peripheral beds of patients with acute coronary syndrome more than in patients with chronic coronary heart disease, which is an additional marker of destabilization of atheromatous structure and active thrombus. In patients with acute myocardial infarction observed a significant decrease in the activity of MMP- 9 in peripheral blood of patients with renal failure and in chronic forms of coronary heart disease, on the contrary, there is increased activity of MMP -9 in patients with renal insufficiency. Product Description popup.authors Дзяк Георгій Вікторович Коваль Олена Акіндинівна Скоромна Анастасія Сергіївна Шаульська Ольга Едуардівна Шевцова Алла Іванівна popup.nrat_date 2020-04-02 Close