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Information × Registration Number 0214U000525, 0108U008699 , R & D reports Title Optimization of diagnostics, treatment, predictors' detecting and developing methods of rehabilitation of children's somatic pathology at various ages. popup.stage_title Head Dudnyk Veronika Michailivna, Registration Date 17-03-2014 Organization Dovganeuk Inna popup.description2 Object of study: chronic hepatitis, acute leukemia, chronic gastro-duodenitis, gastroesophageal reflux disease, juvenile rheumatoid arthritis, chronic glomerulonephritis, and connective tissue dysplasia. Purpose of the study: lipid metabolism in chronic hepatitis C, the structural and functional state of the hepatobiliary system in children with acute leukemia, clinical and morphological features of helicobacter -associated chronic gastroduodenitis in children, hemopoiesis disturbances in chronic glomerulonephritis in children, clinical and morphological features of gastroesophageal reflux disease in older children, peculiarity of the diagnosis of juvenile rheumatoid arthritis in children, clinical symptoms of connective tissue dysplasia in children. Research methods: general clinical and instrumental methods ( abdominal cavity organs ultrasound , Doppler hepatobiliary system, esophagogastroduodenoscopy, daily intragastric pH- metry monitoring); biochemical method for determination of ALT, AST, total bilirubin and its fractions, alkaline phosphatase, total protein, prothrombin index, triglycerides, cholesterol, LDL, HDL, VLDL, immunophenotyping and cytochemical study of bone marrow, ELISA for determination of anti -HCV, HCV-RNA, viral genotype , viral load , AbHCV cor, NS4, NS5 , proof of cagA- positive strains of H. Pylori, determine the content of proinflammatory cytokines in plasma; histological method for assessing morphological picture of the liver morphological changes in the lining of the stomach, esophagus - mucous biopsy, histological method, to determine infection H. pylori - rapid urease test , the degree of colonization of H. pylori - bacterioscopic method, statistical methods. Product Description popup.authors Ізюмець Ольга Іванівна Андрікевич Ірина Іванівна Вижга Юлія Віталіївна Гнатюк Олександр Іванович Гончаров Леонід Іванович Гришко Володимир Григорович Дудник Вероніка Михайлівна Зборовська Ольга Олександрівна Звенігородська Ганна Юріївна Мантак Галина Іванівна Попов Володимир Петрович Руденко Геннадій Миколайович Сінчук Наталія Іванівна Сторожук Ірина Валер'янівна Фурман Валентина Григорівна Шаламай Марина Олександрівна Шангутова Лариса Андріївна popup.nrat_date 2020-04-02 Close