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Information × Registration Number 0214U001251, 0113U005216 , R & D reports Title Elaboration of novel porphyrine nanocomposites for photodynamic therapy and investigation of efficiency and mechanisms of their antitumor action popup.stage_title Head Gamaleia Mykola Fedorovych, Registration Date 24-01-2014 Organization R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology popup.description2 Platinum nanoparticles and new nanocomposite for photodynamic therapy (on the basis of this nanomaterial and photosensitizer chlorin e6) were synthesized. Two fluorescence peaks of platinum nanoparticles were found: at 395-410 nm (excitation ? = 365 nm) and at 500 nm (excitation ? = 470 nm). It was found that malignant cells more actively accumulated nanoparticles than normal cells. Nanoparticles caused more pronounced cytotoxic effect on malignant lymphocytes compared to normal cells. Created nanocomposite was less active than free chlorin e6. Product Description popup.authors Гамалея Микола Федорович Естрела-Льопис Вікторіо Рафаелійович Русінчук Ярослав Іванович Таранець Людмила Петрівна Шишко Євгенія Денисівна popup.nrat_date 2020-04-02 Close