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Information × Registration Number 0214U001827, 0112U001477 , R & D reports Title Systemic and molecular-genetic investigations jf mechanisms hypertrophy and heart failure development popup.stage_title Head Moybenko Olexij Olexijovych, Registration Date 24-07-2014 Organization Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine popup.description2 With the application of modern molecular techniques, new data on the dependence of the level of miR-1 (the mature and immature forms) were obtained. It was found out that it decrease in a remote postinfarction period is associated with a tendency to increase the level of mRNA of target genes, connexin-43 and Bcl2. The changes of mRNA expression cystathione-?-lyase (CBS), cystathione-?-synthase (CBS) and3-mercaptopyruvatesulfotransferase (MPST) in the heart of adult and old rats. The role of melatonin in changes of contractile activity of the rats myocardium and the UCP mPNA expression (mitochondrial uncoupled protein) in the heart tissues. Product Description popup.authors І.М.Маньковська В.Ф.Сагач В.Я.Березовський О.О.Мойбенко Р.І.Янчій popup.nrat_date 2020-04-02 Close