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Information × Registration Number 0214U002819, 0111U002058 , R & D reports Title To Improve Diagnostics and Treatment of Polycystic Ovary Syndrome in Young Women popup.stage_title Head Tatarchuk Tetyana, Доктор медичних наук Registration Date 07-02-2014 Organization State organization "Institute of pediatrics, obstetrics and gynecology NAMS of Ukraine" popup.description2 Object of study: 674 women aged 18 to 35 years. The main group consisted of 554 women with polycystic ovary syndrome (PCOS ), the control group included - 120 healthy women of similar age.Objective: To justify the system for providing medical and preventive care for women with polycystic ovary syndrome by developing an algorithm and its diagnosis as well as differentiated pathogenetic treatment .Methods: epidemiological , medical, statistical, ultrasonographic , imunoassey analisis. Means of measuring: weighing machine VM- 150, ultrasound machine SIEMENS Sonoline-SL400, Analyzer "MSR- 1000", photometer Cobas Mira, "Roche". It was the first investigation of adipocytokine status that demonstrated the role of adipose tissue dysfunction in the mechanism of PCOS development. Also the role of vitamin D deficiency in the genesis of PCOS was proved. Based on the research of carbohydrate metabolism in various clinical and pathogenetic variants of PCOS it was first established that this pathology leads to the formation of insulin resistance not only on the background of obesity, but also in its absence and is a significant factor in the development of metabolic syndrome. This study showed that PCOS is a multifactorial disease that progresses with age. Its key mechanisms are hyperandrogenism, dysfunction of adipose tissue, which causes a variety of clinical and pathogenetic variants of its course. Based on the results of research 22 papers were published, 14 presentations were made and 4 patents for utility model were received. Methodic recommendations are under consideration in the Ministry of Health of Ukraine. Product Description popup.authors Антипкін Ю.Г. Татарчук Т.Ф. popup.nrat_date 2020-04-02 Close