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Information × Registration Number 0214U003328, 0109U002824 , R & D reports Title The associative biomarkers of effectiveness prognosis and the safety of metabolic cardiocytoprotectors and cerebroprotectors in diseases of cardiorespiratory system popup.stage_title Head Yakovleva Olga Aleksandrovna, Registration Date 29-01-2014 Organization Dovganeuk Inna popup.description2 The object of study - pharmacological correction and protection of target organs in diseases of the cardio -respiratory system . Purpose - based on clinical and genetic biomarkers to develop a customized , secure and efficient algorithms for pharmacotherapy of target organs (heart , lungs , brain) in diseases of the cardiorespiratory system. The effectiveness and safety of metabolic and cardio- cerebrovascular protectors in patients with the disease of asthma, hypertension , systemic lupus erythematosus in combination with pulmonary hypertension.  It is proved that NAT2 enzyme activity causes phenotypic polymorphism in its different variants responses to pharmacotherapy of bronchial asthma. Established that Cardonat and Mildronat reduce the level of endogenous intoxication , make lower level indicators troponin I and creatine kinase -MB levels , reduces symptoms and the incidence of ischemia and arrhythmias in the myocardium, improves the course of asthma according controllable and respiratory function . Was used differentiated schemes of treatment pulmonary hypertension by vasodilator Corargin. The effectiveness and safety of Melatonin in combination with complex therapy of hypertension was investigated The efficacy and safety of the combination of valsartan , Neurorubine laktab forte , and folic acid in the pharmacotherapy of hypertension was demonstrated. Product Description popup.authors Жамба Алла Олегівна Півторак Катерина Володимирівна popup.nrat_date 2020-04-02 Close