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Information × Registration Number 0214U003418, 0111U002004 , R & D reports Title Molecular basis of designing preventive and therapeutic antiviral drugs popup.stage_title Head Rybalko S.L., Registration Date 31-01-2014 Organization The L.V. Gromashevsky Institute of Epidemiology and Infectious Diseases AMS of Ukraine popup.description2 The authors proposed a new substance - mimikryny that have unique properties mimicry peptides from viruses, bacteria , toxins, viruses that imitate peptides that are responsible for their pathogenic properties. These properties are the basis of antigenic mimicry mechanism of adjuvant and antiviral activity mimikryniv . The results of the study of molecular biological , physical, chemical, adjuvant and antiviral activity mimikryniv . Determined the amino acid sequences of individual peptides mimikryniv chemically synthesized peptides each consisting of 18 amino acids. Synthesized peptide identified as mimikryn. The results of adjuvant activity mimikryniv, fractions and R18 peptide immunization vaccines against flu, hepatitis and against the herpes virus Varicella zoster, herpes virus recombinant peptide 2 diabetes, and their antiviral activity in models of influenza virus, hepatitis C herpes and HIV in vitro and in vivo. The obtained results can be used to develop new antiviral drugs Product Description popup.authors І. Кожухар Д. Старосила Л. Беньковська Л. Жаркова Н. Іванська О. Васильченко С. Григор"єва С. Дядюн С. Рибалко Т. Калітенко Ю. Порва popup.nrat_date 2020-04-02 Close