Search academic texts

Information × Registration Number 0214U003481, 0111U004737 , R & D reports Title Scientific justification of laboratory model for biological method of diagnostic of transmissive infectious diseases caused by bactiria of Anaplasma, Bartonella, Ehrlichia genes popup.stage_title Head Pokhil Sergiy Ivanovich, Registration Date 04-02-2014 Organization The Mechnikov Research Institute of microbiology and immunology at Kharciv popup.description2 Biological method of the bacterial transmissed infectious agents - anaplasmosis, bartonellosis, ehrlichiosis (AI, BI, EI, accordingly) diagnostic has been worked in fast. Skim-algoritm of it's realization are include such as main stages sectional preparation of the biological material differential genes infectious injections by the preparative patterns to the laboratory animals with the medicament's immunocompromised state (by the way of subcutaneous injection of "Cyclophosphanum ®" in dose - 250 mkg/kg); from the died and mortalated laboratory animals of it's patterns in sectional material-tissue and organs, which potentially more intensive infected by an agents; verification of the etiology AI, BI, EI on experimented mice by a way of the expressly detection with the PCR method's it's agent's in animals blood. Using of the biological method of accumulation of Anaplasma spp., Barthonella spp., Ehrlichia spp. (p<0,05) in tissues and target-organs infectious laboratory animals, that in all have been possibility level to increase of agents AI, BI, EI detection in experimented pattern of biological material of differential genes in 2,7, 2,0 and 4,2 once. Product Description popup.authors Костиря І.А. Круглова Т.А. Липовецька Н.П. Похил С.І. Салогуб Л.Г Тимченко О.М. Торяник І.І. Чигиринська Н.А. Шевченко І.І. Штикер Л.Г popup.nrat_date 2020-04-02 Close