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Information × Registration Number 0214U005279, 0113U003094 , R & D reports Title Enzyme inhibitors: synthesis and biological activity of condensed heterocyclic systems with core pyrimidine popup.stage_title Head Smolii O., Доктор хімічних наук Registration Date 22-12-2014 Organization Institute of Bioorganic Chemistry and Petrochemistry of National Academy of Sciences of Ukraine popup.description2 A new approach to the synthesis of 2-(methylamino)quinoline-3-carboxamides derivatives was developed through hydrolytic cleavage of the pyrimidine ring in pyrimido[4,5-b]quinoline-2,4(1H,3H)-diones (5-deazaalloxazines). The intermediate structures of the condensation of 5-formiluracyl derivatives with substituted anilines were investigated. The conditions for 6 -electron cyclization of 6-arylimino-5-arylaminomethylenpyrimidines in 5-deazaalloxazines were studied. Product Description popup.authors Л.В.Музичка popup.nrat_date 2020-04-02 Close