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Information × Registration Number 0214U005285, 0114U001760 , R & D reports Title Fluorocontaining analogs of glutamate and -aminobutyric acid: synthesis and analysis of modulated influence on the transport of the neurotransmitters in nerve terminals of the brain. popup.stage_title Head Kukhar V.P., Registration Date 22-12-2014 Organization Institute of Bioorganic Chemistry and Petrochemistry of National Academy of Sciences of Ukraine popup.description2 The new synthetic methods of analogs of Pregabalin (Lyrica® ) were developed (the substituents such as CF3, CH2CF3, CHF2CF2, CF3CHF) in racemic and enantiopure forms. The synthesized fluorocontaining analogs of GABA are able to increase the initial velocity of [3H]GABA uptake by synaptosomes. The effect of the analogs was higher then commercial product Pregabalin. Product Description popup.authors І. І. Герус К. В. Тарасенко Н. А. Толмачева Н.Г. Позднякова О. М. Шайтанова Т.О. Борисова popup.nrat_date 2020-04-02 Close
R & D report
Fluorocontaining analogs of glutamate and -aminobutyric acid: synthesis and analysis of modulated influence on the transport of the neurotransmitters in nerve terminals of the brain.
Head: Kukhar V.P.. Fluorocontaining analogs of glutamate and -aminobutyric acid: synthesis and analysis of modulated influence on the transport of the neurotransmitters in nerve terminals of the brain.. (popup.stage: ). Institute of Bioorganic Chemistry and Petrochemistry of National Academy of Sciences of Ukraine. № 0214U005285
1 documents found

Updated: 2026-03-20


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