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Information × Registration Number 0214U005505, 0108U001484 , R & D reports Title The morphological state of the blood cannel and the cell's elements and tissues during the experimenthal atherosclerosis in the genetic therapy condition popup.stage_title Head Piskun Raisa Petrivna, Registration Date 21-01-2014 Organization Dovganeuk Inna popup.description2 This research dedicated to the study of structural and functional changes in the liver, heart and thyroid in experimental atherosclerosis and their genetic correction. The experimenthal atherosclerosis results to the macro- and micromorphometrical chahges of organs indexes, the disturbances of the blood circulation owing to the decrease of the area of the vessels gap and increase of the vessel's wall thikness in compare with the intact group. Structure of these organs is disrupted due to proliferation of the connective tissue, there is degeneration and destruction of organelles. The prophylactic and therapeutic intramuscular injection of the gene apoE for the pathological changes manifest to the positive effect, which contribute to blood circulation improve, restore the linear indexes and liver's ultrastructure. In compare with the therapeutic the prophylactical injection of gene is the most effective. micromorphometrical chahges of organs indexes, the disturbances of the blood 5481 Product Description popup.authors Білошицька Аліна Василівна Піскун Раїса Петрівна popup.nrat_date 2020-04-02 Close