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Information × Registration Number 0214U005597, 0110U001648 , R & D reports Title To obtain and test the new preparations of biologically active high molecular compounds from Basidiomycetes and other objects. popup.stage_title Head Nikitina Olga Akeksandrovna, Registration Date 29-01-2014 Organization M. Gorky Donetsk National Medical University popup.description2 Object of study: higher basidiomycetes strains from mushrooms collected in the wild , purchased in grocery stores. Breeding ground for maintaining cultures of fungi and biologically active compounds. The composition of the culture medium . Sources of nitrogen and carbon supply. Temperature and acid treatment cultivation. Metal ions as stimulants of synthesis of biologically active compounds. Biogenic stimulators of growth and biosynthesis of organisms. Methods of isolation and purification of bioactive biopolymers. Physico -chemical, immunochemical , biological and pharmacological properties of drugs , biologically active biopolymers. Methods: Microbiological . Biological . Biochemical (determination of enzyme activity, protein concentration , sugars , lipids ). Preparative Protein Chemistry ( extraction , precipitation, dialysis, tsetryfuhuvannya , affinity , ion exchange and helhromatohrafiya , freeze drying , electrophoresis ). Immunochemical ( hemagglutination , Precipitation ). Pharmacological ( immunization of animals). Results: A high level of antioxidant activity of fruit bodies tinder flake allows us to consider it as a promising object for creating multi adaptogenic drugs. The influence of culture medium composition on enzyme production by some strains of basidiomycetes Hirschioporus laricinus, as well as the prospects of studying plant of the genus Polygonum in order to obtain drugs from detoksytsiynymy properties.It is proved that the most valuable to obtain polysaccharide complexes of higher basidiomycetes is PolyporussquamosusHuds. : Fr. and Boletusedulis Bull. : Fr. Basidiomycetes - lesser known as a source of lectins. Agaricus bisporus (J.Lge) Imbach, Boletus edulis Bull.: Fr, Lactarius volemus (Fr.) Fr. Needs to study the presence of lectins mycelium of fungi and mushrooms , cultivated on an industrial scale . Fruit bodies of oyster mushroom oyster possess proteolytic and amylolytic activity. For white fruiting bodies of the fungus and mushrooms dvosporovoyi the display of proteolytic properties. And tinder flake found amylolytic activity.The presence of lectins in Herbal teas . Product Description popup.authors Донченко Н.В. Таллер О.Ю. Шинева Н.В. popup.nrat_date 2020-04-02 Close