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Information × Registration Number 0214U005657, 0111U002347 , R & D reports Title To study remout results of diffuse toxic goiter treatment complicated with ophthalmopathy, with the purpose of creation of the programs of prophylaxis and treatment popup.stage_title Head Oliynyk Valeriy Anatolievich, Registration Date 06-02-2014 Organization State Institution "V.P. Komisarenko Institute of Endocrinology and Metabolism оf the Academy of Medical Scienses of Ukraine" popup.description2 Research object: remote results of treatment of oculopathy for patients by a diffuse toxic goitre, risk of her development factors.Aim: on the basis of analysis of flow of disease, efficiency of surgical methods of treatment of the diffuse toxic goitre complicated by an oculopathy, to work out the optimal charts of her prophylaxis and treatment. Methods: questionnaire, clinical, ophthalmology inspection, ULTRASONIC of orbits, hormonal, biochemical, 24-hours monitoring of cardiac rhythm. Results: At most patients(51,7%) an oculopathy developed in 6-8 months after establishment of diagnosis of thyrotoxicosis. The level of antibodies to the receptor of Thyrotropinum for patients with an oculopathy and diffuse toxic goiter considerably exceeds the same index for patients without an oculopathy and decriase in the process of thyreostatic therapy. After surgical treatment in the volume of thyroidectomy for patients regress of displays of oculopathy is marked, decline of levels of antibodies to the receptor of Thyrotropinum already in 6 months after an operation. Efficiency and safety of the use of chart pulstherapy Methylprednisolonum are well-proven in a dose 750 mgs/24-hours, that conducts to регресу displays of oculopathy, to the decline of levels of antibodies to the receptor of Thyrotropinum and upgrading of life of patients.Degree of introduction : the articles, lectures, patents. Application domain: endocrinology, ophthalmology, family medicine. Product Description popup.authors Булдигіна Юлія Валеріївна Корзун Юлія Василівна Кузьминська Лариса Антонівна Любкіна Марія Миколаївна Олійник Валерій Анатолійович Сологуб Нелля Віталіївна Стаценко Олександр Андрійович Терехова Галина Миколаївна popup.nrat_date 2020-04-02 Close