Search academic texts

Information × Registration Number 0214U005704, 0111U002396 , R & D reports Title Investigation of new 1,4- benzodiazepine-2-one esters hydrolysis using free and immobilized enzymatic systems of animals popup.stage_title Head Romanovskaya І.І., Доктор біологічних наук Registration Date 17-02-2014 Organization A.V.Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine popup.description2 Сarboxylesterase - containing microsomal fraction were isolated from pig tissues, with a help of which the enantioselective hydrolysis of 3-hydroxy-1,4-benzodiazepin-2-one esters was accomplished. The S-enantiomers of some substrates were obtained, their molecular and crystalline structures , affinity to central benzodiazepin receptors were studied. Using the polymeric supports of natural and syndetic origin the immobilized preparations of pig liver microsomal fraction were obtained Product Description popup.authors Є.А. Шестеренко А.М. Овсепян Н.О.Іллюшко О.В. Севастьянов С.С. Декіна popup.nrat_date 2020-04-02 Close