Search academic texts

Information × Registration Number 0214U005910, 0111U010257 , R & D reports Title Develop a program of prevention and treatment of complications in patients depending on the stage of burn disease popup.stage_title Head Jernov Olexandr Andriyovich, Registration Date 26-12-2014 Organization Kiev Research Institute of Haematolojy and Blood Transfusion popup.description2 1.The object of study - 169 hospital charts of patients with burns desease and 90 - patients with deformations and contractures of different localizations, 72 patients with deep and vast burns a from 10% to 60% surface of body which was conducted early surgical treatment and 45 patients with the expressed cicatrical deformations and contractures of body and extremities. 2.Methods of researches: clinical, haematological, biochemical, immunological. The structure of complications is certain depending on the stage of burn disease. The complications from the side of the cardiovascular system, respiratory distress syndrome, acute cardiovascular and bud insufficiency, head cerebral edema were dominant in shock stage . The generalization of the systemic inflammatory response, pneumonia, toxic myocarditis and development of poliorganic insufficiency were observed in toxemia. In septikotoxemia - septic and autoimmune complications. In the stage of reconvalescence- the development of scar deformities and contractures, ulcer scars. The generalization of the inflammatory reaction is the starting point for the development of complications of thermal injury.TNF / ІL-10 and cortisol / FRI were chosen for there estimation. Subsequent stage is the formation of immunosuppression and generalization of infection. Catabolic changes in connective tissue underlie osteodeficit states and pathological scar formation. This developed program of early prediction, prevention and treatment of thermal injuries complications, which includes operations in the early acute phase of injury, laboratory monitoring, new technologies and methods of surgical interventions in the stage of reconvalescence, allowed to improve treatments results of 1.3 times, reduce the number of strains in 1.7 times and reduce the disability of patients 2.3 times. . Medicine. Product Description popup.authors Боярська Г.М. Жернов А.О. Коваленко О.М. Козинець Г.П. Осадча О.І. Циганков В.П. Шевченко І.Є. popup.nrat_date 2020-04-02 Close