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Information × Registration Number 0214U005926, 0110U005552 , R & D reports Title Investigation of tumor microenvironment modifying effect on magnetization, dispersity, biocompatibility and stability of magnetic fluids on the basis of complex ferromagnetic oxides popup.stage_title Head Osynsky Sergy Petrovych, Registration Date 26-12-2014 Organization R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology popup.description2 Magnetic fluids (MF) on the basis of ferromagnetic materials with spinel structure (magnetit) and perovskite (manganite) were synthesized. It was determined pH dependence of magnetit effect when it was combined with alternating magnetic field. The influence of MF pH on its effects was shown. The dependence of distribution of magnetit nanoparticles from MF dose injected into tumor was determined. The enhancement of neutrophiles and macrophages number in tumor after MF administration was shown. It indicates the development of inflammatory reaction. The preliminary preclinical investigations of manganite MF was performed. Product Description popup.authors Бубновська Лариса Микитівна Ганусевич Ірина Іванівна Гуменюк Ліля Дмитрівна Ковельська Антоніна Василівна Мамонтова Леся Анатолієвна Осинський Сергій Петрович popup.nrat_date 2020-04-02 Close