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Information × Registration Number 0214U005949, 0110U004745 , R & D reports Title Investigation of the molecular mechanisms of the course of Alzheimer's disease at the molecular and cellular levels and their pharmacological correction popup.stage_title Head Kostyuk Olena Platonivna ( 2010-2012), Skryl Vyacheslav Mikhailovich (2012-2014), Registration Date 29-12-2014 Organization Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine popup.description2 Using the cytological method and confocal microscopy, the effect of inhibitor of ?-secretase Deshydroxy LY- 411 575 on hippocampal neurons in control and on the cells, which were incubated with beta 1-42-amyloid within 24 hours (cellular model of Alzheimer's disease), compared with the corresponding values in control. It was found that LY- 411 575 increased survival of neurons in the hippocampus in modeling Alzheimer's disease. Product Description popup.authors Кравенська Євгенія Вікторівна Лук"янець Олена Олександрівна Шкриль В"ячеслав Михайлович Яворська Олена Миколаївна popup.nrat_date 2020-04-02 Close
R & D report
Investigation of the molecular mechanisms of the course of Alzheimer's disease at the molecular and cellular levels and their pharmacological correction
Head: Kostyuk Olena Platonivna ( 2010-2012), Skryl Vyacheslav Mikhailovich (2012-2014). Investigation of the molecular mechanisms of the course of Alzheimer's disease at the molecular and cellular levels and their pharmacological correction. (popup.stage: ). Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine. № 0214U005949
1 documents found

Updated: 2026-03-25


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