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Information × Registration Number 0214U006243, 0113U002842 , R & D reports Title Catalytic Michael reaction for synthesis of new biologically active compounds popup.stage_title Head Voitenko Zoia Vsevolodivna, Доктор хімічних наук Registration Date 25-02-2014 Organization Taras Shevchenko Kiev university popup.description2 A new method for the preparation of the adducts of aromatic hetero nucleophiles (NH, SH, ОH) to the activated C=C bond of N-aryl-substituted maleimides using Michael reaction was developed. Pyrrolidine-2 ,5-dione moiety can be successfully used in the design of promising anti-TB drugs. The introduction of this structural fragment showed a significant increase in the activity of compounds against the growth of M.tuberculosis. Product Description popup.authors Єгорова Тетяна Володимирівна Виборний Олег Анатолійович Войтенко Зоя Всеволодівна Кисіль Андрій Іванович Крикун Сергій Олександрович Матвіюк Тетяна Володимирівна popup.nrat_date 2020-04-02 Close