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Information × Registration Number 0214U006833, 0112U004114 , R & D reports Title Interactions of peptide compounds from natural venoms with ionotropic purinergic receptors and acid-sensing ion channels popup.stage_title Head Krishtal O.A., Registration Date 26-02-2014 Organization Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine popup.description2 Two new peptide ?-AnmTX Hcr 1b-1 and ?-AnmTX Ugr 9-1 of sea anemone toxins possessing inhibitory action on channels ASIC3 using chromatographic methods were isolated biological activity of all three ligands in electrophysiological experiments on channels ASIC3was measured. For two of them was shown a unique ability to suppress the amplitude of both fast and slow component of the current ASIC3. Pain in two in vivo models demonstrated for the analgesic effect of peptide Ugr 9-1. Product Description popup.authors Волкова Т.М. Кришталь О.О. Максимюк О.П. Фісюнов О.П. Хмиз В.В. popup.nrat_date 2020-04-02 Close