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Information × Registration Number 0214U008289, 0114U006082 , R & D reports Title Kinetics and the mechanism of interaction between the protein of virus HIV-1 nucleocapside and ligands: site-selective investigation by fluorescent probes, sensitive to environment popup.stage_title Head Zaporozhets Olga Antonivna, Registration Date 30-12-2014 Organization Taras Shevchenko Kiev university popup.description2 The possibility of using N-carboxymethyl-N-(8-quinolylcarbamoylmethyl)aminoacetic acid as a fluorescent probe for testing of the inactivate efficiency of zinc fingers of the protein NCp7 by drugs was studied. It was established that on interaction of probe with peptides, mixed-ligand complexes with high intrinsic fluorescence were formed, which disappear at destabilization of the zinc fingers of the protein. This fact can be used to test and validate new drugs efficiency. Product Description popup.authors Линник Ростислав Петрович popup.nrat_date 2020-04-02 Close