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Information × Registration Number 0215U000108, 0111U010268 , R & D reports Title Develop methods to improve the treatment of patients with atrophic diseases of the mucous membrane of the upper respiratory tract based on the use of stem cell therapy popup.stage_title Head Minin Yu.V., Registration Date 23-01-2015 Organization Kiyv Research Institute of Otolaryngology named after prof. O.S.Kolomiychenko popup.description2 The experimental models of the atrophic changes of the nasal cavity mucous membrane of infectious and chemical origin were confirmed by the clinical and morphological studies. The methods of isolation and culture of multipotent mesenchymal stromal cells (MMSC) provide the opportunity of receiving morphologically and phenotypically unchanged cells on the second passage level for the following parenteral administration injection to the animals during the experiment. The use of umbilical cord and adipose tissue MMSC for reparative process stimulation in the mucous membranes in the nasal cavities of test/experimental animals, where atrophic changes had been induced, was proved successful on the basis of morphological, morphometric and histochemical studies. Product Description popup.authors Дерябіна О. Карась А.Ф. Карась Г.А. Кучеренко Т.І. Мінін Ю.В. Тимченко С.В. Чайка С.П. popup.nrat_date 2020-04-02 Close